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Giulia Liberati - Principal Investigator

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The main objective of my research is to characterize how transient and sustained pain are represented in the human brain, taking advantage of the high temporal and spatial resolution of intracerebral electroencephalography (iEEG). I am particularly interested in investigating the role of the human insula in nociception and pain perception, as several findings suggest that this brain region plays a crucial role in the integration of sensory, affective, and cognitive dimensions of pain.

Group members

Publications

2024

Commentary : Advancements in noninvasive brain stimulation: exploring repetitive transcranial magnetic stimulation of the posterior superior insula for pain relief.

Pain

Liberati G.

in press

2024

Electroencephalogram synchronization measure as a predictive biomarker of Vagus nerve stimulation response in refractory epilepsy: A retrospective study

PLoS One

Danthine V, Cottin L, Berger A, Germany Morrison EI, Liberati G, Ferrao Santos S, Delbeke J, Nonclercq A, El Tahry R

19(6):e0304115.

2024

Cue-based modulation of pain stimulus expectation: do ongoing oscillations reflect changes in pain perception? A registered report.

R Soc Open Sci

Leu C, Glineur E, Liberati G

11(6):240626.

2023

The role of ongoing oscillation in pain perception: Absence of modulation by a concomitant arithmetic task

Cortex

Leu C, Courtin A, Cussac C, Liberati G.

168:114-129.

2022

Characterization of vagus nerve stimulation-induced pupillary responses in epileptic patients

PDF

Brain Stimulation

Vespa S, Stumpp L, Liberati G, Delbeke J, Nonclercq A, Mouraux A, El Tahry R

in press.

2021

Vagus Nerve Stimulation elicits sleep EEG desynchronization and network changes in responder patients in epilepsy

Neurotherapeutics

Vespa S, Heyse J, Stumpp L, Liberati G, Ferrao Santos S, Rooijakkers H, Nonclercq A, Mouraux A, van Mierlo P, El Tahry R.

18(4):2623-2638.

2021

Transcutaneous auricular VNS applied to experimental pain: A paired behavioral and EEG study using thermonociceptive CO2 laser.

PLoS One

Dumoulin M, Liberati G, Mouraux A, Santos SF, El Tahry R.

16(7):e0254480.

2020

Insular responses to transient painful and non-painful thermal and mechanical spinothalamic stimuli recorded using intracerebral EEG

Nature: Scientific Reports

Liberati G, Mulders D, Algoet M, van den Broeke EN, Ferrao Santos S, Ribeiro Vaz JG, Raftopoulos C, Mouraux A.

10: 22319

2019

Brain-Machine Interface in Chronic Stroke: Randomized Trial Long-Term Follow-up

PDF

Neurorehabilitation and Neural Repair

Ramos-Murguialday A, Curado MR, Broetz D, Yilmaz Ö, Brasil FL, Liberati G, Garcia-Cossio E, Cho W, Caria A, Cohen LG, Birbaumer N.

33(3):188-198

2018

Tonic thermonociceptive stimulation selectively modulates ongoing neural oscillations in the human posterior insula: evidence from intracerebral EEG

Neuroimage

Liberati G, Algoet M, Ferrao Santos S, Ribeiro-Vaz JG, Raftopoulos C, Mouraux A.

188:70-83

2018

Habituation of phase-locked local field potentials and gamma-band oscillations recorded from the human insula

Nature: Scientific Reports

Liberati G, Algoet M, Klöcker A, Ferrao Santos S, Ribeiro-Vaz JG, Raftopoulos C, Mouraux A.

8(1): 8265

2017

Gamma-band oscillations preferential for nociception can be recorded in the human insula

Cerebral Cortex

Liberati G, Klöcker A, Algoet M, Mulders D, Safronova MM, Ferrao Santos S, Vaz JG, Raftopoulos C, Mouraux A.

28(10):3650-3664.

2016

EEG frequency tagging using ultra-slow periodic heat stimulation of the skin reveals cortical activity specifically related to C fiber thermonociceptors

Neuroimage

Colon E, Liberati G, Mouraux A.

146:266-274

2016

Nociceptive local field potentials recorded from the human insula are not specific for nociception

PLoS Biology

Liberati G, Klocker A, Safronova MM, Ferrao Santos S, Ribeiro Vaz JG, Raftopoulos C, Mouraux A.

14(1):e1002345

2015

Residual Upper Arm Motor Function Primes Innervation of Paretic Forearm Muscles in Chronic Stroke after Brain-Machine Interface (BMI) Training

PDF

PLoS One

Curado MR, Cossio EG, Broetz D, Agostini M, Cho W, Brasil FL, Yilmaz O, Liberati G, Lepski G, Birbaumer N, Ramos-Murguialday A.

10(10):e0140161

Institute of Neuroscience (IONS) - Université catholique de Louvain (UCL)

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NOCIONS : PAIN RESEARCH AT UCLOUVAIN

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