André Mouraux - Principal investigator (IONS/COSY)




Using non-invasive functional neuroimaging techniques such as electroencephalography (EEG) and functional magnetic resonance imaging (fMRI), combined with novel techniques to selectively activate specific classes of nociceptive afferents, the research performed by the team of André Mouraux (IONS/COSY) follows two main axes. First, to understand how the human brain processes nociceptive sensory input and how this leads to the perception of pain. Second, to understand the plastic changes in nociceptive pathways that occur after inflammation, injury or sustained nociceptive input that induce peripheral and central sensitization and may underlie the development of chronic pain in humans.



Publications
Strength, extent and duration of secondary hyperalgesia induced by high-frequency electrical stimulation of the foot compared to the volar forearm of healthy human volunteers
PLoS One
Lebrun L, Lenoir C, Leone C, van den Broeke EN, Caspani O, Schilder A, Pelz B, Truini A, Treede RD, Mouraux A
20(2):e0318934.
2025
A pain research strategy for Europe: A European survey and position paper of the European Pain Federation EFIC
Eur J Pain
Pickering G, O'Keeffe M, Bannister K, Becker S, Cottom S, Cox FJ, Eisenberg E, Finn DP, Forget P, Graven-Nielsen T, Kalso E, Kocot-Kepska M, Leite-Almeida H, Lopez-Garcia JA, Meeus M, Mouraux A, Pereira B, Puljak L, Reneman MF, Rohde I, Sotiropoulos I, Skidmore N, Tölle TR, Todorovic ST, Truini A, Vowles KE, Pogatzki-Zahn E, Garcia-Larrea L, Fullen BM
29(1):e4767.
2024
How visual experience shapes body representation
Cognition
Shahzad I, Occelli V, Giraudet E, Azañón E, Longo MR, Mouraux A, Collignon O.
254:105980.
2024
Effect of limb position change on capsaicin-evoked pain: evidence of interplays between the vascular and nociceptive systems?
Eur J Pain
Courtin AS, Knaepen, C, Mouraux A, van Neerven SGA
in press.
2024
Studying the effect of expectations on high-frequency electrical stimulation-induced pain and pinprick hypersensitivity
J Pain
Gousset S, Cayrol T, Papleux M, Meulders A, Mouraux A, van den Broeke EN
in press
Systematic review and co-ordinate based meta-analysis to summarize the utilization of functional brain imaging in conjunction with human models of peripheral and central sensitization
Eur J Pain
Clarke S, Rogers R, Wanigasekera V, Fardo F, Pia H, Nochi Z, Macian N, Leray V, Finnerup NB, Pickering G, Mouraux A, Truini A, Treede RD, Garcia-Larrea L, Tracey I.
in press.
2023
Intra-operative electroencephalogram frontal alpha-band spectral analysis and postoperative delirium in cardiac surgery: A prospective cohort study
Eur J Anaesthesiol
Khalifa C, Lenoir C, Robert A, Watremez C, Kahn D, Mastrobuoni S, Aphram G, Ivanoiu A, Bonhomme V, Mouraux A, Momeni M.
40(10):777-787.
2023
Pinprick-induced gamma-band oscillations are not a useful electrophysiological marker of pinprick hypersensitivity in humans
Clin Neurophysiol
Gousset S, Torta DM, Mouraux A, Lambert J, van den Broeke EN.
53:102-110.
2023
Influence of skin type and laser wavelength on laser evoked potentials
Eur J Pain
Frahm KS, Gervasio S, Arguissain F, Mouraux A
in press.