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André Mouraux - Principal investigator (IONS/COSY)

Using non-invasive functional neuroimaging techniques such as electroencephalography (EEG) and functional magnetic resonance imaging (fMRI), combined with novel techniques to selectively activate specific classes of nociceptive afferents, the research performed by the team of André Mouraux (IONS/COSY) follows two main axes. First, to understand how the human brain processes nociceptive sensory input and how this leads to the perception of pain. Second, to understand the plastic changes in nociceptive pathways that occur after inflammation, injury or sustained nociceptive input that induce peripheral and central sensitization and may underlie the development of chronic pain in humans.

Publications

2013

Unmasking the obligatory components of nociceptive event-related brain potentials

Journal of Neurophysiology

Mouraux A, De Paepe AL, Marot E, Plaghki L, Iannetti GD, Legrain V.

110(10):2312-24

2013

Primary Sensory Cortices Contain Distinguishable Spatial Patterns of Activity for Each Sense

Nature Communications

Liang M, Mouraux A, Hu L, Iannetti GD.

1.540972222

2013

Psychophysical and electrophysiological evidence for nociceptive dysfunction in CRPS

Pain

Caty G, Hu L, Legrain V, Plaghki L, Mouraux A.

154(11):2521-8

2013

Beyond metaphor: Contrasting mechanisms of social and physical pain

TRENDS in Cognitive Sciences

Iannetti GD, Salomons TV, Moayedi M, Mouraux A, Davis KD.

17(8): 371-8

2013

Clinical usefulness and feasibility of time-frequency analysis of chemosensory event-related potentials

Rhinology

Huart C, Rombaux P, Hummel T, Mouraux A.

51(3): 210-21

2013

Reliable EEG responses to the selective activation of C-fibre afferents using a temperature-controlled infrared laser stimulator in conjunction with an adaptive staircase algorithm

Pain

Jankovski A, Plaghki L, Mouraux A.

154(9): 1578-87

2013

Shielding cognition from nociception with working memory

Cortex

Legrain V, Crombez G, Plaghki L, Mouraux A.

49(7):1922-34

2013

Bypassing primary sensory cortices - a direct thalamocortical pathway for transmitting salient sensory information

Cerebral Cortex

Liang M, Mouraux A, Iannetti GD.

23(1): 1-11

2013

Novelty is not enough: laser-evoked potentials are determined by stimulus saliency, not absolute novelty

Journal of Neurophysiology

Ronga I, Valentini E, Mouraux A, Iannetti GD.

109(3):692-701

2012

Selective neuronal entrainment to the beat and meter embedded in a musical rhythm

Journal of Neuroscience

Nozaradan S, Peretz I, Mouraux A.

32(49):17572-81

2012

Steady-state evoked potentials to study the processing of tactile and nociceptive somatosensory input in the human brain

Neurophysiologie Clinique - Clinical Neurophysiology

Colon E, Legrain V, Mouraux A.

42(5):315-23

2012

Estimation of intraepidermal fiber density by the detection rate of nociceptive laser stimuli in normal and pathological conditions

Neurophysiologie Clinique - Clinical Neurophysiology

Mouraux A, Ragé M, Bragard D, Plaghki L.

42(5): 281-91

2012

Activating selectively and reliably nociceptive afferents with concentric electrode stimulation: yes we can, provided that low stimulus intensities are used

Clinical Neurophysiology

Legrain V, Mouraux A.

124(2): 424

2012

Automated single-trial assessment of laser-evoked potentials as an objective functional diagnostic tool for the nociceptive system

Clinical Neurophysiology

Hatem SM, Hu L, Ragé M, Gierasimowicz-Fontana A, Plaghki L, Bouhassira D, Attal N, Iannetti GD, Mouraux A.

123(12): 2437-45

2012

Gamma-band oscillations in the primary somatosensory cortex - a direct and obligatory correlate of subjective pain intensity

Journal of Neuroscience

Zhang ZG, Lu H, Hung YS, Mouraux A, Iannetti GD.

32(22): 7429-38

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