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André Mouraux - Principal investigator (IONS/COSY)

Using non-invasive functional neuroimaging techniques such as electroencephalography (EEG) and functional magnetic resonance imaging (fMRI), combined with novel techniques to selectively activate specific classes of nociceptive afferents, the research performed by the team of André Mouraux (IONS/COSY) follows two main axes. First, to understand how the human brain processes nociceptive sensory input and how this leads to the perception of pain. Second, to understand the plastic changes in nociceptive pathways that occur after inflammation, injury or sustained nociceptive input that induce peripheral and central sensitization and may underlie the development of chronic pain in humans.

Publications

2020

New insights into cutaneous laser stimulation – dependency on skin and laser type

Neuroscience

Frahm KS, Gervasio S, Arguissain F, Mouraux A.

448:71-84.

2020

Assessing thermal sensitivity using transient heat and cold stimuli combined with a Bayesian adaptive method in a clinical setting: a proof of concept study

European Journal of Pain

Courtin AS, Maldonado Slootjes S, Caty G, Hermans MP, Plaghki L, Mouraux A.

24(9):1812-1821.

2020

Investigating perceptual simultaneity between nociceptive and visual stimuli by means of temporal order judgments

Neuroscience Letters

Manfron L, Filbrich L, Nijs E, Mouraux A, Legrain V.

735:135156.

2020

Central sensitization of nociceptive pathways demonstrated by robot-controlled pinprick-evoked brain potentials

Clinical Neurophysiology

van den Broeke EN, de Hemptinne P, Mercken M, Torta DM, Lambert J, Mouraux A.

131(10):2491-2498.

2020

Within- and between-session reliability of secondary hyperalgesia induced by electrical high-frequency stimulation

European Journal of Pain

Cayrol T, Lebleu J, Mouraux A, Roussel N, Pitance L, van den Broeke E.

24(8):1585-1597.

2020

Does motor cortex engagement during movement preparation differentially inhibit nociceptive processing in patients with chronic whiplash associated disorders, chronic fatigue syndrome and healthy controls? An experimental study

Journal of Clinical Medicine

Goudman L, Mouraux A, Daenen L, Nijs J, Cras P, Roussel N, Moens M, Lenoir D, Coppieters I, Huysmans E, De Kooning M.

9(5): E1520

2020

Capsaicin-induced skin desensitization differentially affects A-delta and C-fiber mediated heat sensitivity

Frontiers in Pharmacology

van Neerven SGA, Mouraux A.

0.885416667

2020

Processing of laser-evoked potentials in patients with chronic whiplash-associated disorders, chronic fatigue syndrome, and healthy controls: a case-control study

Pain Medicine

Goudman L, Daenen L, Mouraux A, Nijs J, Cras P, Roussel N, Moens M, Coppieters I, Huysmans E, De Kooning M.

21(10):2553-2563.

2020

Dynamics of the perception and EEG signals triggered by tonic warm and cool stimulation

PLoS ONE

Mulders D, de Bodt C, Lejeune N, Dufour A, Verleysen M, Mouraux A.

15(4):e0231698

2020

Early gamma-oscillations as correlate of localized nociceptive processing in primary sensorimotor cortex

Journal of Neurophysiology

Heid C, Mouraux A, Treede RD, Schuh-Hofer S, Rupp A, Baumgärtner U.

123(5):1711-1726

2020

Adaptation of the Sniffin Sticks Test in South-Kivu

European Annals of Oto-rhino-laryngology, Head and Neck diseases

Balungwe P, Huart C, Matanda R, Bisimwa G, Mouraux A, Rombaux P.

S1879-7296(20)30032-6

2020

Mechanisms linking olfactory impairment and risk of mortality

Frontiers in Neuroscience

Van Regemorter V , Hummel T, Rosenzweig F, Mouraux A, Rombaux P, Huart C.

0.680555556

2020

Burst-like conditioning electrical stimulation is more efficacious than continuous stimulation for inducing secondary hyperalgesia in humans

Journal of Neurophysiology

Gousset S, Mouraux A, van den Broeke EN.

123(1):323-328

2020

The focus of spatial attention during the induction of central sensitization can modulate the subsequent development of secondary hyperalgesia

Cortex

Filbrich L, van den Broeke E, Legrain V, Mouraux .

124:193-203

2019

Development of a new psychophysical method to assess intranasal trigeminal chemosensory function

Rhinology

Huart C, Hummel T, Kaehling C, Konstantinidis I, Hox V, Mouraux A, Rombaux P.

57(5): 375-384

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