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Giulia Liberati - Principal Investigator

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The main objective of my research is to characterize how transient and sustained pain are represented in the human brain, taking advantage of the high temporal and spatial resolution of intracerebral electroencephalography (iEEG). I am particularly interested in investigating the role of the human insula in nociception and pain perception, as several findings suggest that this brain region plays a crucial role in the integration of sensory, affective, and cognitive dimensions of pain.

Publications

2023

The role of ongoing oscillation in pain perception: Absence of modulation by a concomitant arithmetic task

Cortex

Leu C, Courtin A, Cussac C, Liberati G.

168:114-129.

2022

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Characterization of vagus nerve stimulation-induced pupillary responses in epileptic patients

Brain Stimulation

Vespa S, Stumpp L, Liberati G, Delbeke J, Nonclercq A, Mouraux A, El Tahry R

in press.

2021

Vagus Nerve Stimulation elicits sleep EEG desynchronization and network changes in responder patients in epilepsy

Neurotherapeutics

Vespa S, Heyse J, Stumpp L, Liberati G, Ferrao Santos S, Rooijakkers H, Nonclercq A, Mouraux A, van Mierlo P, El Tahry R.

18(4):2623-2638.

2021

Transcutaneous auricular VNS applied to experimental pain: A paired behavioral and EEG study using thermonociceptive CO2 laser.

PLoS One

Dumoulin M, Liberati G, Mouraux A, Santos SF, El Tahry R.

16(7):e0254480.

2020

Insular responses to transient painful and non-painful thermal and mechanical spinothalamic stimuli recorded using intracerebral EEG

Nature: Scientific Reports

Liberati G, Mulders D, Algoet M, van den Broeke EN, Ferrao Santos S, Ribeiro Vaz JG, Raftopoulos C, Mouraux A.

10: 22319

2019

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Brain-Machine Interface in Chronic Stroke: Randomized Trial Long-Term Follow-up

Neurorehabilitation and Neural Repair

Ramos-Murguialday A, Curado MR, Broetz D, Yilmaz Ö, Brasil FL, Liberati G, Garcia-Cossio E, Cho W, Caria A, Cohen LG, Birbaumer N.

33(3):188-198

2018

Tonic thermonociceptive stimulation selectively modulates ongoing neural oscillations in the human posterior insula: evidence from intracerebral EEG

Neuroimage

Liberati G, Algoet M, Ferrao Santos S, Ribeiro-Vaz JG, Raftopoulos C, Mouraux A.

188:70-83

2018

Habituation of phase-locked local field potentials and gamma-band oscillations recorded from the human insula

Nature: Scientific Reports

Liberati G, Algoet M, Klöcker A, Ferrao Santos S, Ribeiro-Vaz JG, Raftopoulos C, Mouraux A.

8(1): 8265

2017

Gamma-band oscillations preferential for nociception can be recorded in the human insula

Cerebral Cortex

Liberati G, Klöcker A, Algoet M, Mulders D, Safronova MM, Ferrao Santos S, Vaz JG, Raftopoulos C, Mouraux A.

28(10):3650-3664.

2016

EEG frequency tagging using ultra-slow periodic heat stimulation of the skin reveals cortical activity specifically related to C fiber thermonociceptors

Neuroimage

Colon E, Liberati G, Mouraux A.

146:266-274

2016

Nociceptive local field potentials recorded from the human insula are not specific for nociception

PLoS Biology

Liberati G, Klocker A, Safronova MM, Ferrao Santos S, Ribeiro Vaz JG, Raftopoulos C, Mouraux A.

14(1):e1002345

2015

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Residual Upper Arm Motor Function Primes Innervation of Paretic Forearm Muscles in Chronic Stroke after Brain-Machine Interface (BMI) Training

PLoS One

Curado MR, Cossio EG, Broetz D, Agostini M, Cho W, Brasil FL, Yilmaz O, Liberati G, Lepski G, Birbaumer N, Ramos-Murguialday A.

10(10):e0140161

2015

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Extracting neurophysiological signals reflecting users' emotional and affective responses to BCI use: A systematic literature review

NeuroRehabilitation

Liberati G, Federici S, Pasqualotto E.

37(3):341-58

2015

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Assistive device with conventional, alternative, and brain-computer interface inputs to enhance interaction with the environment for people with amyotrophic lateral sclerosis: a feasibility and usability study

Archives of Physical Medicine and Rehabilitation

Schettini F, Riccio A, Simione L, Liberati G, Caruso M, Frasca V, Calabrese B, Mecella M, Pizzimenti A, Inghilleri M, Mattia D, Cincotti F.

96(3 Suppl):S46-53

2015

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Developing brain-computer interfaces from a user-centered perspective: Assessing the needs of persons with amyotrophic lateral sclerosis, caregivers, and professionals

Applied Ergonomics

Liberati G, Pizzimenti A, Simione L, Riccio A, Schettini F, Inghilleri M, Mattia D, Cincotti F.

50:139-46

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