Sabien van Neerven - former postdoc (UCL MoveIn)
The general objective of my project was to characterize the effects of topical capsaicin treatment on the changes in function and structure of nociceptive pathways associated with the development of chronic neuropathic pain and/or central sensitization. The project was translational, from bench to bedside, combining work performed in an animal model of neuropathic pain and work performed in patients suffering from chronic post-operative pain.
Publications
2024
Effect of limb position change on capsaicin-evoked pain: evidence of interplays between the vascular and nociceptive systems?
Eur J Pain
Courtin AS, Knaepen, C, Mouraux A, van Neerven SGA
in press.
2018
Cell-enrichment with olfactory ensheathing cells has limited local extra beneficial effects on nerve regeneration supported by the nerve guide Perimaix
Journal of Tissue Engineering and Regenerative Medicine
Boecker AH, Bozkurt A, Kim BS, Altinova H, Tank J, Deumens R, Tolba R, Weis J, Brook GA, Pallua N, van Neerven S.
in press
2017
Inflammation-associated regulation of RGS in astrocytes and putative implication in neuropathic pain
Journal of Neuroinflammation
Doyen PJ, Vergouts M, Pochet A, Desmet N, van Neerven S, Brook G, Hermans E.
14(1):209
2017
Clinical and biometrical 12 months follow up study in patients after reconstruction of the sural nerve biopsy defect by the collagen-based nerve guide Neuromaix
European Journal of Medical Research
Bozkurt A, Claeys KG, Schrading S, Rose JV, Sellhaus B, Schulz JB, Weis J, Pallua N and van Neerven S.
22(1): 34
2016
Functional recovery not correlated with axon regeneration through OEC-seeded scaffolds in a model of acute SCI
Journal of Tissue Engineering and Regenerative Medicine
Altinova H, Möllers S, Deumens R, Gerardo-Nava J, Führmann T, van Neerven S, Bozkurt A, Heschel I, Weis J, and Brook GA.
13(5): 585-600
2016
Pre-differentiation of mesenchymal stromal cells in combination with a microstructured nerve guide supports peripheral nerve regeneration in the rat sciatic nerve model
European Journal of Neuroscience
Boecker AH, van Neerven S, Scheffel J, Tank J, Altinova H, Seidensticker K, Deumens R, Tolba R, Weis J, Brook GA, Pallua N and Bozkurt A.
43(3): 404-16
2016
Efficient bridging of 20 mm rat sciatic nerve lesions with a longitudinally micro-structured collagen scaffold
Biomaterials
Bozkurt A, Boecker A, Tank J, Altinova H, Deumens R, Dabhi C, Tolba R, Weis J, Brook GA, Pallua N, van Neerven SG.
75:112-22
2016
Two-component collagen nerve guides support axonal regeneration in the rat peripheral nerve injury model
Journal of Tissue Engineering and Regenerative Medicine
van Neerven SG, Haastert-Talini K, Boecker A, Schriever T, Dabhi C, Claeys K, Deumens R, Brook GA, Weis J, Pallua N, Bozkurt A.
2016
Pre-differentiation of mesenchymal stromal cells in combination with a microstructured nerve guide supports peripheral nerve regeneration in the rat sciatic nerve model
European Journal of Neuroscience
Boecker AH, van Neerven SG, Scheffel J, Tank J, Altinova H, Seidensticker K, Deumens R, Tolba R, Weis J, Brook GA, Pallua N, Bozkurt A.
43(3):404-16
2014
Human Schwann cells seeded on a novel collagen-based microstructured nerve guide survive, proliferate, and modify neurite outgrowth
BioMed Research International
van Neerven SG, Krings L, Haastert-Talini K, Vogt M, Tolba RH, Brook G, Pallua N, Bozkurt A.
2014:493823
2014
Differences in degradation behavior of two non-cross-linked collagen barrier membranes: an in vitro and in vivo study
Clinical Oral Implantations Research
Bozkurt A, Apel C, Sellhaus B, van Neerven S, Wessing B, Hilgers RD, Pallua N.
25(12):1403-11
2014
The proximal medial sural nerve biopsy model: a standardised and reproducible baseline clinical model for the translational evaluation of bioengineered nerve guides
BioMed Research International
Bozkurt A, van Neerven SG, Claeys KG, ODey DM, Sudhoff A, Brook GA, Sellhaus B, Schulz JB, Weis J, Pallua N.
2014:121452
2013
Schwann cell migration and neurite outgrowth are influenced by media conditioned by epineurial fibroblasts
Neuroscience
van Neerven SG, Pannaye P, Bozkurt A, Van Nieuwenhoven F, Joosten E, Hermans E, Taccola G, Deumens R.
252:144-53