NOCIONS all publications
NOCIONS all publications
Emmanuel Hermans - Principal investigator (IONS/CEMO)
Group :
The research group of Prof. Emmanuel Hermans (IONS/CEMO) has a long-standing expertise in the use of animal models to study the neuroinflammation and plastic changes of the central nervous system induced by neurotrauma, and its involvement in the development of neuropathic pain. His laboratory has experience in the production of animal models of neuropathic pain, the techniques used to study the pain behaviour of these animals, and the immune-histological techniques to characterize the glial activation and changes in nociceptive pathways at peripheral, spinal and supra-spinal level.
Publications
2015
Inhibition of the regulator of G protein signalling RGS4 in the spinal cord decreases neuropathic hyperalgesia and restores cannabinoid CB1 receptor signalling
British Journal of Pharmacology
Bosier B, Doyen PJ, Brolet A, Muccioli GG, Ahmed E, Desmet N, Hermans E, Deumens R.
in press.
2015
Modulation of spinal glial reactivity by intrathecal PPF is not sufficient to inhibit mechanical allodynia induced by nerve crush
Neuroscience Research
Gallo A, Dimiziani A, Damblon J, Michot B, Des Rieux A, De Kock M, Hermans E, Deumens R.
in press.
2015
The anti-inflammatory peptide stearyl-norleucine-VIP delays disease onset and extends survival in a rat model of inherited amyotrophic lateral sclerosis
Experimental Neurology
Goursaud S, Schäfer S, Dumont AO, Vergouts M, Gallo A, Desmet N, Deumens R, Hermans E.
in press.
2014
Influence of intrathecal delivery of bone marrow-derived mesenchymal stem cells on spinal inflammation and pain hypersensitivity in a rat model of peripheral nerve injury
Journal of Neuroinflammation
Schäfer S, Berger JV, Deumens R, Goursaud S, Hanisch UK, Hermans E.
in press.
2013
Schwann cell migration and neurite outgrowth are influenced by media conditioned by epineurial fibroblasts
Neuroscience
van Neerven SG, Pannaye P, Bozkurt A, Van Nieuwenhoven F, Joosten E, Hermans E, Taccola G, Deumens R.
in press.
2013
Up-regulation of spinal microglial Iba-1 expression persists after resolution of neuropathic pain hypersensitivity
Neuroscience Letters
Leinders M, Knaepen L, De Kock M, Sommer C, Hermans E, Deumens R.
in press.
2011
Enhanced neuroinflammation and pain hypersensitivity after peripheral nerve injury in rats expressing mutated superoxide dismutase 1
Journal of Neuroinflammation
Berger JV, Deumens R, Goursaud S, Schäfer S, Lavandhomme P, Joosten EA, Hermans E.
in press.